Solutions

• Platelet Additive Solution   • Red Cell Additive Solution   • Anticoagulant Solution
 

Platelet Additive Solution

SSP+ the most suitable PAS on the market, Safe platelets through saved plasma

Description

The Platelet Additive Solution SSP+ “PAS-E” is designed to partially replace plasma in the preparation and storage of buffy-coat derived platelet concentrates or apheresis platelet units. The recommended ratio is up to 80% SSP+ / 20% plasma. The solution enables platelets to be stored at 22°C ± 2°C, under gentle agitation, for up to 7 days following collection and according to local regulations.

Benefits of SSP+:

Specifications:

Instructions for use

Bibliography

1 Comparison of in vitro characteristics of apheresis-derived PC with low Residual plasma during storage in different platelet additive solutions., Nogawa et al, Vox Sang 2011; 101(Suppl.2):25.

2 In vitro properties of platelets stored in three platelet additive solutions. Tynngard N, Trinks M, Berlin G. Transfusion, published online, Vox Sanguinis 2012; 102, 32–39.

3 Reactions and platelet increments after transfusion of platelet concentrates in plasma or an additive solution: a prospective, randomized study; J. de Wildt-Eggen et al., TRANSFUSION April 2000, Volume 40.

4 Reduced rate of adverse reactions to plasma reduced pooled platelet units possible role of minor incompatible transfusions; F.Wagner, W.Adamo, Vox Sanguinis 2006.

5 Ringwald J, Zimmermann R, Eckstein R. The new generation of platelet additive solution for storage at 22°C: Development and current experience. Transfus Med Rev Vol 2006;20(2):158-164)

6 Seltsam A, Müller TH. UVC irradiation for pathogen reduction of platelet concentrates and plasma. Transfus Med Hemother 2011;38:43-54.

7 Mohr H, Gravemann U, Bayer A, Müller TH. Sterilization of platelet concentrates at production scale by irradiation with short-wave ultraviolet light. Transfusion 2009;49:1956-1963.

8 Mohr H, Steil L, Gravemann U, Thiele T, Hammer E, Greinacher A, Müller TH, Volker U. A novel approach to pathogen reduction in platelet concentrates using short-wave ultraviolet light. Transfusion 2009;49:2612-2624.

9 Sandgren P, Tolksdorf F, Struff WG, Gulliksson H. In vitro effects on platelets irradiated with short-wave ultraviolet light without any additional photoactive reagent using the THERAFLEX UV-Platelets method. Vox Sang 2011;101:35-43.

 

Red Cell Additive Solution

SAG-Mannitol:

Description:

The additive solution Saline Adenine Glucose –Mannitol is designed for the suspension and storage of red blood cells, at 4° C ± 2°C for a 42 days period, after collection. The solution is used with apheresis and can be added to red cell after washing.

Specifications:

Instructions for use

 

Anticoagulant Solution

Anticoagulant solutions for Apheresis Collection: ACD Formula A

Description:

Acid Citrate Dextrose formula A is an anticoagulant solution added to whole blood during automated collection.

Specifications:

Instructions for use

 

Anticoagulant Solution

Anticoagulant solutions for Apheresis Collection: Citrate 4%

Description:

Citrate 4% is an anticoagulant solution added to whole blood during automated collection.

Specifications:

Instructions for use